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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIPK3
All Species:
8.48
Human Site:
S170
Identified Species:
37.33
UniProt:
Q9Y572
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y572
NP_006862.2
518
56887
S170
L
S
T
F
Q
G
G
S
Q
S
G
T
G
S
G
Chimpanzee
Pan troglodytes
XP_001169864
518
56818
S170
L
S
T
F
Q
G
G
S
Q
S
G
T
G
S
G
Rhesus Macaque
Macaca mulatta
XP_001114079
518
56653
S170
L
S
T
F
Q
G
G
S
Q
S
G
T
A
S
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZL0
486
53318
K145
P
L
L
H
R
D
L
K
P
S
N
I
L
L
D
Rat
Rattus norvegicus
Q9Z2P5
478
52215
P137
C
Y
L
H
S
L
N
P
S
L
L
H
R
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085647
719
80009
N173
A
K
W
N
G
L
S
N
S
H
E
L
S
L
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
89.5
N.A.
N.A.
57.7
56.7
N.A.
N.A.
N.A.
25.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
93
N.A.
N.A.
67.3
66.8
N.A.
N.A.
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
N.A.
N.A.
13.3
0
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% A
% Cys:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
17
0
0
0
0
0
0
0
17
34
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% E
% Phe:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
17
50
50
0
0
0
50
0
34
0
34
% G
% His:
0
0
0
34
0
0
0
0
0
17
0
17
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% I
% Lys:
0
17
0
0
0
0
0
17
0
0
0
0
0
0
0
% K
% Leu:
50
17
34
0
0
34
17
0
0
17
17
17
17
34
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
0
17
17
0
0
17
0
0
0
0
% N
% Pro:
17
0
0
0
0
0
0
17
17
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
50
0
0
0
50
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
17
0
0
0
0
0
0
0
17
0
17
% R
% Ser:
0
50
0
0
17
0
17
50
34
67
0
0
17
50
0
% S
% Thr:
0
0
50
0
0
0
0
0
0
0
0
50
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _